Deleted In Azoospermia 4 (DAZ4) (AA 90-119) antibody

Details for Product No. ABIN5532902
Antigen
Epitope
AA 90-119
9
8
8
7
3
3
1
1
Reactivity
Human
52
19
19
4
3
3
2
2
2
2
Host
Rabbit
51
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
33
24
19
13
7
1
1
Options
Immunogen This DAZ4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human DAZ4.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen
Alternative Name DAZ4 (DAZ4 Antibody Abstract)
Background This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Molecular Weight 65 kDa
Gene ID 57135
UniProt Q86SG3
Application Notes For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier Images
Image no. 1 for anti-Deleted In Azoospermia 4 (DAZ4) (AA 90-119) antibody (ABIN5532902) Western blot analysis in A549 cell line lysates (35ug/lane).
Image no. 2 for anti-Deleted In Azoospermia 4 (DAZ4) (AA 90-119) antibody (ABIN5532902) DAZ4 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded h...