Deleted In Azoospermia 4 (DAZ4) (AA 89-120), (Middle Region) antibody

Details for Product No. ABIN951840
Antigen
Epitope
AA 89-120, Middle Region
10
8
7
7
3
2
1
1
Reactivity
Human
52
19
19
4
3
3
2
2
2
2
Host
Rabbit
51
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
33
24
19
13
7
1
Options
Immunogen KLH conjugated synthetic peptide between 89-120 amino acids from the Central region of Human DAZ4. Genename: DAZ4
Isotype Ig Fraction
Specificity This antibody recognizes Human DAZ4 (Center).
Purification Protein A column, followed by peptide affinity purification
Antigen
Alternative Name DAZ4 (DAZ4 Antibody Abstract)
Background This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].Synonyms: Deleted in azoospermia protein 4
Molecular Weight 64785 Da
Gene ID 57135
NCBI Accession NP_001005375
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-Deleted In Azoospermia 4 (DAZ4) (AA 89-120), (Middle Region) antibody (ABIN951840) Formalin fixed, paraffin embedded human testis tissue stained with DAZ4 Antibody  fol...
Image no. 2 for anti-Deleted In Azoospermia 4 (DAZ4) (AA 89-120), (Middle Region) antibody (ABIN951840) Western blot analysis of DAZ4 Antibody  in A549 cell line lysates (35ug/lane). This d...