CRP antibody

Catalog No. ABIN5596712

Supplier Product No.: 209-1132-0100

Product Details anti-CRP Antibody

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CRP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Supplier Product No.: 209-1132-0100

Supplier: Rockland

Purpose: CRP Antibody

Cross-Reactivity (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Capsular Reactive Protein (CRP) [Human Serum].

Characteristics: Synonyms: goat anti-CRP Antibody, C reactive protein pentraxin related antibody, CRP antibody, MGC88244 antibody, PTX 1 antibody, PTX1 antibody

Purification: This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Immunogen:

Immunogen: Capsular Reactive Protein (CRP) [Human Serum]

Immunogen Type: Native Protein

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry Dilution: 1:1,000 - 1:5,000

Application Note: Anti-CRP Antibody has been tested by dot blot and western blot and is suitable for ELISA and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1:2,000 - 1:10,000

ELISA Dilution: 1:4,000 - 1:40,000

Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution Volume: 100 μL

Reconstitution Buffer: Restore with deionized water (or equivalent)

Concentration: 10.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: CRP (CRP Products)

Background: Background: CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.

Gene ID: 1401

NCBI Accession: NP_000558

UniProt: P02741

Pathways: Carbohydrate Homeostasis