MORC3 antibody

Catalog No. ABIN5596952

Supplier Product No.: 100-401-n97

Product Details anti-MORC3 Antibody

Target: MORC3 (MORC Family CW-Type Zinc Finger 3 (MORC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MORC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Supplier Product No.: 100-401-n97

Supplier: Rockland

Purpose: Morc3 Antibody

Cross-Reactivity (Details): The antibody is specific for human Morc3 in expressed cell lysates.

Characteristics: Synonyms: rabbit anti-Morc3 Antibody, MORC family CW-type zinc finger protein 3, Protein microrchidia, Morc antibody, Nuclear matrix protein 2, Zinc finger CW-type coiled-coil domain protein 3, ZCWCC3, NXP2

Purification: Morc3 antibody was prepared from monospecific antiserum by delipidation and defibrination.

Sterility: Sterile filtered

Immunogen:

Immunogen: Morc3 whole rabbit serum was prepared by repeated immunizations with a human Morc3 recombinant protein.

Immunogen Type: Recombinant Protein

Application Details

Application Notes:

Application Note: Anti-Morc3 Antibody is tested for use in Western Blot and suitable for ChIP and IF. Specific conditions for reactivity should be optimized by the end user.   Expect a band approximately 107.1 kDa in size corresponding Morc3 by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1000-1:5000

ELISA Dilution: 1:20,000-1:50,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 70 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

References for anti-MORC3 antibody (ABIN5596952)

Li, Yen, Pastor, Johnston, Du, Shew, Liu, Ho, Stender, Clark, Burlingame, Daxinger, Patel, Jacobsen: "Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 35, pp. E5108-16, (2018) (PubMed).

Target Details for MORC3

Target: MORC3 (MORC Family CW-Type Zinc Finger 3 (MORC3))

Alternative Name: MORC3 (MORC3 Products)

Background: Background: The Morc (microrchidia) family of proteins are ATPases of the GHKL family. They have been implicated in transcriptional repression of genes and transposons, and higher order organization of DNA within the nucleus. Morc antibodies are ideal for researchers interested in Epigenetics, Cancer, and Cell cycle research.

Gene ID: 23515

NCBI Accession: NP_056173

UniProt: Q14149

Pathways: Maintenance of Protein Location