ASNA1 antibody (AA 239-348)

Catalog No. ABIN559968

Product Details anti-ASNA1 Antibody

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Binding Specificity: AA 239-348

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ASNA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant ASNA1.

Sequence: PEQTTFICVC IAEFLSLYET ERLIQELAKC KIDTHNIIVN QLVFPDPEKP CKMCEARHKI QAKYLDQMED LYEDFHIVKL PLLPHEVRGA DKVNTFSALL LEPYKPPSAQ

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ASNA1 (NP_004308, 239 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2H3

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ASNA1 antibody (ABIN559968)

Ott, Marques, Funk, Bailer: "Asna1/TRC40 that mediates membrane insertion of tail-anchored proteins is required for efficient release of Herpes simplex virus 1 virions." in: Virology journal, Vol. 13, Issue 1, pp. 175, (2016) (PubMed).

Baron, Pedrioli, Tyagi, Johnson, Wood, Fountaine, Wightman, Alexandru: "VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase." in: BMC biology, Vol. 12, pp. 39, (2014) (PubMed).

Rabu, Wipf, Brodsky, High: "A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 283, Issue 41, pp. 27504-13, (2008) (PubMed).

Target Details for ASNA1

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Alternative Name: ASNA1 (ASNA1 Products)

Background: Full Gene Name: arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Synonyms: ARSA-I,ARSA1,MGC3821

Gene ID: 439

NCBI Accession: NM_004317

Pathways: Positive Regulation of Peptide Hormone Secretion