ABCC11 antibody (AA 343-372)

Catalog No. ABIN5647634

Product Details anti-ABCC11 Antibody

Target: ABCC11 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11))

Binding Specificity: AA 343-372

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 343-372 from the human protein was used as the immunogen for this ABCC11 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ABCC11 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ABCC11

Target: ABCC11 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11))

Alternative Name: MRP8 / ABCC11 (ABCC11 Products)

Synonyms: EWWD antibody, MRP8 antibody, WW antibody, ATP binding cassette subfamily C member 11 antibody, ABCC11 antibody

Background: ATP-binding cassette sub-family C member 11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.

UniProt: Q96J66