ABCC11 Products
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11))
Categories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
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Featured ABCC11 Categories
ABCC11 Antibodies
High quality antibodies with extensive validation data.
ABCC11 ELISA Kits
Reliable ELISA kits for a wide range of species.
ABCC11 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABCC11 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, FACS
Validations
- (5)
Cat. No.
ABIN302164
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
Cat. No.
ABIN529878
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7144903
Quantity
100 μL
Datasheet
Datasheet
Recommended ABCC11 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953977
Quantity
96 tests
Datasheet
Datasheet
Recommended ABCC11 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305451
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305450
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3088043
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ABCC11 products
: "Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells." in: Biochemical and biophysical research communications, Vol. 394, Issue 4, pp. 1098-104, (2010) (PubMed).: "Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system." in: Neuroscience, Vol. 137, Issue 4, pp. 1247-57, (2006) (PubMed).
Synonyms and alternative names related to ABCC11
ATP binding cassette subfamily C member 11 (ABCC11), EWWD, MRP8, WWProtein level used designations for ABCC11
- ATP-binding cassette protein C11
- ATP-binding cassette sub-family C member 11
- ATP-binding cassette transporter MRP8
- ATP-binding cassette transporter sub-family C member 11
- multi-resistance protein 8
- multidrug resistance-associated protein 8
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