FCAR antibody (AA 22-227)

Catalog No. ABIN5684138

Product Details anti-FCAR Antibody

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Binding Specificity: AA 22-227

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCAR antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD89 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD89 (AA: 22-227) expressed in E. Coli.

Clone: 2F9D8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: CD89 (FCAR Products)

Background:

Description: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: FCAR, FcalphaRI, CTB-61M7.2

Molecular Weight: 32.3kDa

Gene ID: 2204

HGNC: 2204

UniProt: P24071