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CISD2 antibody

CISD2 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5700515
  • Target See all CISD2 Antibodies
    CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
    Reactivity
    • 12
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 14
    • 1
    Rabbit
    Clonality
    • 14
    • 1
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    This CISD2 antibody is un-conjugated
    Application
    • 11
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Immunogen
    CDGSH iron sulfur domain 2
    Isotype
    IgG
    Top Product
    Discover our top product CISD2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01718(CISD2 antibody) at dilution of 1:1000

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
    Alternative Name
    CISD2 (CISD2 Products)
    Synonyms
    ERIS antibody, Miner1 antibody, NAF-1 antibody, WFS2 antibody, ZCD2 antibody, 1500009M05Rik antibody, 1500026J14Rik antibody, 1500031D15Rik antibody, AI848398 antibody, B630006A20Rik antibody, Noxp70 antibody, Zcd2 antibody, RGD1566242 antibody, zgc:64148 antibody, eris antibody, miner1 antibody, wfs2 antibody, zcd2 antibody, cisd2 antibody, BcDNA:RE49709 antibody, Dmel\\CG1458 antibody, CDGSH iron sulfur domain 2 antibody, CDGSH iron sulfur domain 2 L homeolog antibody, CDGSH iron sulfur domain 2 S homeolog antibody, CISD2 antibody, Cisd2 antibody, cisd2 antibody, cisd2.L antibody, cisd2.S antibody
    Background
    Synonyms:CDGSH2, ERIS, ZCD2 Background:Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
    Molecular Weight
    13-15 kDa
    Gene ID
    493856
    UniProt
    Q8N5K1
    Pathways
    Activation of Innate immune Response
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