MKS1 antibody (N-Term)

Catalog No. ABIN5708506

Product Details anti-MKS1 Antibody

Target: MKS1 (Meckel Syndrome, Type 1 (MKS1))

Binding Specificity: AA 90-124, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 90-124 from human MKS1 was used as the immunogen for the MKS1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the MKS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MKS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MKS1

Target: MKS1 (Meckel Syndrome, Type 1 (MKS1))

Alternative Name: MKS1 / Meckel syndrome type 1 protein (MKS1 Products)

Background: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

UniProt: Q9NXB0