MKS1 antibody

Catalog No. ABIN7469490

This Rabbit Polyclonal antibody specifically detects MKS1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MKS1 antibody (ABIN7469490)

Target: MKS1 (Meckel Syndrome, Type 1 (MKS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MKS1 Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MKS1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.63 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MKS1

Target: MKS1 (Meckel Syndrome, Type 1 (MKS1))

Alternative Name: MKS1

Background:

Synonyms: MKS transition zone complex subunit 1 , BBS13 , JBTS28 , MES , MKS , POC12

Background: The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 65 kDa

Gene ID: 54903

UniProt: Q9NXB0