Granulin antibody (AA 281-336)
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- Target See all Granulin (GRN) Antibodies
- Granulin (GRN)
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Binding Specificity
- AA 281-336
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Granulin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- DVKCDMEVSC PDGYTCCRLQ SGAWGCCPFT QAVCCEDHIH CCPAGFTCDT QKGTCE
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 281-336 of human Granulin (NP_002078.1).
- Isotype
- IgG
- Top Product
- Discover our top product GRN Primary Antibody
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anti-Granulin (GRN) (AA 361-585) antibody
GRN Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Granulin (GRN) (AA 31-269) antibodyGRN Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Granulin (GRN) (Center) antibodyGRN Reactivity: Human, Mouse, Rat WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Granulin (GRN) antibodyGRN Reactivity: Human WB Host: Rabbit Monoclonal unconjugated
anti-Granulin (GRN) (AA 44-255) antibodyGRN Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Granulin (GRN) (AA 451-550) antibodyGRN Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Granulin (GRN) (AA 563-591), (C-Term) antibodyGRN Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB44397 unconjugated
anti-Granulin (GRN) (AA 494-593) antibodyGRN Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Granulin (GRN) (AA 494-593) antibodyGRN Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1F5 unconjugated
anti-Granulin (GRN) (AA 21-120) antibodyGRN Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Granulin (GRN)
- Alternative Name
- GRN (GRN Products)
- Background
- Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.,GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN,granulins,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,GRN
- Molecular Weight
- 44 kDa/46 kDa/63 kDa
- Gene ID
- 2896
- UniProt
- P28799
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