Granulin Antibodies

Nguyen, Nguyen, Zhang, Devireddy, Zhou, Karydas, Xu, Miller, Rigo, Ferguson, Huang, Walther, Farese: "Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 12, pp. E2849-E2858, (2018) (PubMed).

Holler, Taylor, Deng, Kukar: "Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations." in: eNeuro, Vol. 4, Issue 4, (2018) (PubMed).

Bandey, Chiou, Huang, Tsai, Tu: "Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness." in: Oncogene, Vol. 34, Issue 14, pp. 1853-64, (2015) (PubMed).

Thurner, Fadle, Regitz, Kemele, Klemm, Zaks, Stöger, Bette, Carbon, Zimmer, Assmann, Murawski, Kubuschok, Held, Preuss, Pfreundschuh: "The molecular basis for development of proinflammatory autoantibodies to progranulin." in: Journal of autoimmunity, Vol. 61, pp. 17-28, (2015) (PubMed).

Elkabets, Gifford, Scheel, Nilsson, Reinhardt, Bray, Carpenter, Jirström, Magnusson, Ebert, Pontén, Weinberg, McAllister: "Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice." in: The Journal of clinical investigation, Vol. 121, Issue 2, pp. 784-99, (2011) (PubMed).

Kahle, Gulbahce, Shaw, Lim, Hill, Barabási, Zoghbi: "Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia." in: Human molecular genetics, Vol. 20, Issue 3, pp. 510-27, (2011) (PubMed).

Li, Chen, Gong, Hu, Li, Lin, Lin, Liu, Wu: "Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish." in: The Journal of biological chemistry, Vol. 285, Issue 52, pp. 41001-9, (2010) (PubMed).

Ghetti, Spina, Murrell, Huey, Pietrini, Sweeney, Wassermann, Keohane, Farlow, Grafman: "In vivo and postmortem clinicoanatomical correlations in frontotemporal dementia and parkinsonism linked to chromosome 17." in: Neuro-degenerative diseases, Vol. 5, Issue 3-4, pp. 215-7, (2008) (PubMed).

Ho, Ip, Cheung, Lee, Chan, Wong, Fan: "Granulin-epithelin precursor as a therapeutic target for hepatocellular carcinoma." in: Hepatology (Baltimore, Md.), Vol. 47, Issue 5, pp. 1524-32, (2008) (PubMed).

Lu, Serrero: "Stimulation of PC cell-derived growth factor (epithelin/granulin precursor) expression by estradiol in human breast cancer cells." in: Biochemical and biophysical research communications, Vol. 256, Issue 1, pp. 204-7, (1999) (PubMed).