PTPRE antibody (AA 20-200)

Catalog No. ABIN6146460

Product Details anti-PTPRE Antibody

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Binding Specificity: AA 20-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LRGNETTADS NETTTTSGPP DPGASQPLLA WLLLPLLLLL LVLLLAAYFF RFRKQRKAVV STSDKKMPNG ILEEQEQQRV MLLSRSPSGP KKYFPIPVEH LEEEIRIRSA DDCKQFREEF NSLPSGHIQG TFELANKEEN REKNRYPNIL PNDHSRVILS QLDGIPCSDY INASYIDGYK E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human PTPRE (NP_006495.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRE

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Alternative Name: PTPRE (PTPRE Products)

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.,PTPRE,HPTPE,PTPE,R-PTP-EPSILON,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,PTPRE

Molecular Weight: 71 kDa/74 kDa/80 kDa

Gene ID: 5791

UniProt: P23469