Interferon Regulatory Factor 2 (IRF2) antibody

Details for Product No. ABIN6257284
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
129
76
55
9
9
7
6
6
6
4
3
2
2
1
Host
Rabbit
109
12
9
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
5
4
4
4
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
94
48
32
14
13
8
7
6
5
3
3
2
1
1
1
1
Options
Immunogen A synthesized peptide
Isotype IgG
Specificity IRF2 Antibody detects endogenous levels of total IRF2
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Antigen
Alternative Name IRF2 (IRF2 Antibody Abstract)
Background

Description: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

Gene: IRF2

Molecular Weight 47 kDa
Gene ID 3660
UniProt P14316
Application Notes WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Interferon Regulatory Factor 2 (IRF2) antibody (ABIN6257284) ABIN6274172 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyd...
Image no. 2 for anti-Interferon Regulatory Factor 2 (IRF2) antibody (ABIN6257284) ABIN6274172 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeab...
Image no. 3 for anti-Interferon Regulatory Factor 2 (IRF2) antibody (ABIN6257284) Western blot analysis of extracts from various samples, using IRF2 Antibody. Lane 1: ...
Image no. 4 for anti-Interferon Regulatory Factor 2 (IRF2) antibody (ABIN6257284) Western blot analysis of extracts from Jurkat cells using IRF2 antibody.