CYP2A6 antibody (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6)

Catalog No. ABIN6258062

Product Details anti-CYP2A6 Antibody

Target:

CYP2A6

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2A6 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)

Specificity: Cytochrome P450 2A6 Antibody detects endogenous levels of total Cytochrome P450 2A6

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500~1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for CYP2A6

Target:

CYP2A6

Alternative Name: Cytochrome P450 2A6 (CYP2A6 Antibody Abstract)

Synonyms: CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB, cyp2a6, cytochrome P450 family 2 subfamily A member 6, cytochrome P450 2A6, cytochrome P450 family 2 subfamily A member 6 L homeolog, CYP2A6, cyp2a6.L

Background:

Description: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Gene: CYP2A6

Molecular Weight: 56 kDa

Gene ID: 1548

UniProt: P11509