CYP2A6 antibody (N-Term)

Catalog No. ABIN7184442

Product Details anti-CYP2A6 Antibody

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2A6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human Cytochrome P450 2A6.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP2A6

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Alternative Name: CYP2A6 (CYP2A6 Products)

Synonyms: CPA6 antibody, CYP2A antibody, CYP2A3 antibody, CYPIIA6 antibody, P450C2A antibody, P450PB antibody, cyp2a6 antibody, cytochrome P450 family 2 subfamily A member 6 antibody, cytochrome P450 2A6 antibody, cytochrome P450 family 2 subfamily A member 6 L homeolog antibody, CYP2A6 antibody, cyp2a6.L antibody

Background:

Background: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Miles J.S., ic Acids Res. 17:2907-2917(1989).
Yamano S., Biochemistry 29:1322-1329(1990).
Saito S., J. Hum. Genet. 48:249-270(2003).

Aliases: Coumarin 7 hydroxylase antibody, Coumarin 7-hydroxylase antibody, CP2A6_HUMAN antibody, CPA6 antibody, CYP2A antibody, CYP2A3 antibody, CYP2A6 antibody, CYPIIA6 antibody, Cytochrome P450 2A6 antibody, Cytochrome P450 IIA3 antibody, Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody, Cytochrome P450(I) antibody, Cytochrome P450, family 2 subfamily A polypeptide 6 antibody, Flavoprotein linked monooxygenase antibody, P450C2A antibody, P450PB antibody, Xenobiotic monooxygenase antibody

UniProt: P11509