PPP1R10 antibody (C-Term)

Catalog No. ABIN6258637

Product Details anti-PPP1R10 Antibody

Target: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: PPP1R10 Antibody detects endogenous levels of total PPP1R10.

Predicted Reactivity: Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PPP1R10, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for PPP1R10

Target: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Alternative Name: PPP1R10 (PPP1R10 Products)

Background:

Description: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).

Gene: PPP1R10

Molecular Weight: 99 kDa

Gene ID: 5514

UniProt: Q96QC0

Pathways: Protein targeting to Nucleus