PPP2R3C antibody (Protein Phosphatase 2, Regulatory Subunit B'', gamma)

Catalog No. ABIN6259560

Product Details anti-PPP2R3C Antibody

Target:

PPP2R3C

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R3C antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)

Specificity: PPP2R3C Antibody detects endogenous levels of total PPP2R3C

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500~1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for PPP2R3C

Target:

PPP2R3C

Alternative Name: PPP2R3C (PPP2R3C Antibody Abstract)

Synonyms: 4930511A21Rik, 5730412A08Rik, G4-1, G5pr, C14orf10, RGD1309207, zgc:55473, protein phosphatase 2, regulatory subunit B'', gamma, protein phosphatase 2 regulatory subunit B''gamma, Ppp2r3c, PPP2R3C, ppp2r3c

Background:

Description: May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.

Gene: PPP2R3C

Molecular Weight: 53 kDa

Gene ID: 55012

UniProt: Q969Q6

Pathways: PI3K-Akt Signaling