PPP2R3C antibody (C-Term)

Catalog No. ABIN6259560

Product Details anti-PPP2R3C Antibody

Target: PPP2R3C (Protein Phosphatase 2, Regulatory Subunit B'', gamma (PPP2R3C))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: PPP2R3C Antibody detects endogenous levels of total PPP2R3C.

Predicted Reactivity: Zebrafish,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PPP2R3C, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PPP2R3C

Target: PPP2R3C (Protein Phosphatase 2, Regulatory Subunit B'', gamma (PPP2R3C))

Alternative Name: PPP2R3C (PPP2R3C Products)

Background:

Description: May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.

Gene: PPP2R3C

Molecular Weight: 53 kDa

Gene ID: 55012

UniProt: Q969Q6

Pathways: PI3K-Akt Signaling