Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) antibody

Details for Product No. ABIN6263968
Antigen
  • Ph-4
  • RGD1311848
  • EGLN4
  • HIFPH4
  • P4H-TM
  • PH-4
  • PH4
  • PHD4
  • 4933406E20Rik
  • AI853847
  • BB128974
  • prolyl 4-hydroxylase, transmembrane
  • prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
  • shisa family member 5
  • P4htm
  • P4HTM
  • SHISA5
Reactivity
Human, Mouse (Murine), Rat (Rattus)
63
48
37
4
4
4
4
3
3
2
2
1
Host
Rabbit
62
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
3
3
3
3
3
3
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
26
26
6
5
4
3
1
Options
Immunogen A synthesized peptide derived from human P4HTM
Isotype IgG
Specificity P4HTM Antibody detects endogenous levels of total P4HTM
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Antigen
Alternative Name P4HTM (P4HTM Antibody Abstract)
Background

Description: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Gene: P4HTM

Molecular Weight 57 kDa
Gene ID 54681
UniProt Q9NXG6
Application Notes WB 1:1000-3000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) antibody (ABIN6263968) Western blot analysis of P4HTM using Jurkat whole cell lysates
Did you look for something else?