SLC30A7 antibody (N-Term)

Catalog No. ABIN6266145

Product Details anti-SLC30A7 Antibody

Target: SLC30A7 (Solute Carrier Family 30 (Zinc Transporter), Member 7 (SLC30A7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC30A7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: ZnT7 Antibody detects endogenous levels of total ZnT7.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZnT7, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC30A7

Target: SLC30A7 (Solute Carrier Family 30 (Zinc Transporter), Member 7 (SLC30A7))

Alternative Name: SLC30A7 (SLC30A7 Products)

Background:

Description: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).

Gene: SLC30A7

Molecular Weight: 65 kDa

Gene ID: 148867

UniProt: Q8NEW0

Pathways: Peptide Hormone Metabolism, Transition Metal Ion Homeostasis, SARS-CoV-2 Protein Interactome