Tyrosinase  (TYR) antibody

Details for Product No. ABIN6297624
Antigen
  • sandy
  • zgc:109705
  • TYR
  • TYRO
  • tyr
  • LOC100136546
  • CMM8
  • OCA1A
  • OCAIA
  • SHEP3
  • albino
  • c
  • skc35
  • C
  • tyrosinase
  • TYRosinase
  • tyrosinase S homeolog
  • tyr
  • tyr-5
  • tyr.S
  • TYR
  • Celal_3121
  • Halhy_4121
  • Mesop_2736
  • LOC100136546
  • Tyr
Reactivity
Human
256
45
39
10
7
6
6
5
2
2
2
2
2
1
1
1
1
Host
Mouse
139
133
2
Clonality
Monoclonal
Conjugate
Un-conjugated
10
6
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (IHC)
126
125
99
81
81
63
57
23
20
15
13
12
11
10
3
1
Options
Purpose Mouse anti-Human Tyrosinase Antibody [IHC only]
Immunogen Recombinant Tyrosinase protein was used as the immunogen for this antibody.
Specificity Cytoplasmic
Purification Recombinant Tyrosinase protein was used as the immunogen for this antibody.
Antigen
Alternative Name Tyrosinase (TYR Antibody Abstract)
Background

Target Description: Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

Gene Symbol: TYR

Gene ID 7299
UniProt P14679
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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