TYR antibody

Catalog No. ABIN6265828

Product Details anti-TYR Antibody

Target: TYR (Tyrosinase (TYR))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Specificity: Tyrosinase Antibody detects endogenous levels of total Tyrosinase

Cross-Reactivity: Human, Monkey, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Tyrosinase

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: Tyrosinase (TYR Products)

Synonyms: sandy antibody, zgc:109705 antibody, TYR antibody, TYRO antibody, tyr antibody, LOC100136546 antibody, CMM8 antibody, OCA1A antibody, OCAIA antibody, SHEP3 antibody, albino antibody, c antibody, skc35 antibody, C antibody, tyrosinase antibody, TYRosinase antibody, tyrosinase S homeolog antibody, tyr antibody, tyr-5 antibody, tyr.S antibody, TYR antibody, Celal_3121 antibody, Halhy_4121 antibody, Mesop_2736 antibody, LOC100136546 antibody, Tyr antibody

Background:

Description: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.

Gene: TYR

Molecular Weight: 70 kDa

Gene ID: 7299

UniProt: P14679