ECM1 antibody

Catalog No. ABIN6297629

Product Details anti-ECM1 Antibody

Target: ECM1 (Extracellular Matrix Protein 1 (ECM1))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ECM1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purpose: Mouse anti-Human/Rat Secretory Component Antibody [Sodium Azide Free]

Specificity: Cell surface and cytoplasmic

Purification: Secretory Component protein isolated from human colostrum was used as the immunogen for this Secretory Component antibody.

Immunogen: Secretory Component protein isolated from human colostrum was used as the immunogen for this Secretory Component antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for ECM1

Target: ECM1 (Extracellular Matrix Protein 1 (ECM1))

Alternative Name: Extracellular matrix protein 1 (ECM1 Products)

Synonyms: URBWD antibody, ECM antibody, EMILIN4 antibody, GPIa* antibody, MMRN antibody, AI663821 antibody, p85 antibody, extracellular matrix protein 1 antibody, multimerin 1 antibody, ECM1 antibody, MMRN1 antibody, Ecm1 antibody

Background:

Target Description: This mAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

Gene Symbol: ECM1

Gene ID: 1893

UniProt: Q16610