ECM1 antibody (Middle Region)

Catalog No. ABIN2782635

The Rabbit Polyclonal anti-ECM1 antibody (ABIN2782635) specifically detects ECM1 in IHC and WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit samples.

Quick Overview for ECM1 antibody (Middle Region) (ABIN2782635)

Target: ECM1 (Extracellular Matrix Protein 1 (ECM1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECM1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-ECM1 Antibody

Binding Specificity: Middle Region

Purpose: ECM1 Antibody - middle region

Sequence: QDRSQGGWGH RLDGFPPGRP SPDNLNQICL PNRQHVVYGP WNLPQSSYSH

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ECM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ECM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46447-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ECM1

Target: ECM1 (Extracellular Matrix Protein 1 (ECM1))

Alternative Name: ECM1

Background:

Background Information: This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Gene Name: extracellular matrix protein 1

Alternative Symbols: URBWD

Protein Name: Extracellular matrix protein 1

Molecular Weight: 18kDa

Gene ID: 1893

NCBI Accession: NP_073155

UniProt: Q16610