Prolactin Receptor antibody (PRLR)

Details for Product anti-PRLR Antibody No. ABIN6297635
Target
Reactivity
Human
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Host
Mouse
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Clonality
Monoclonal
Conjugate
This Prolactin Receptor antibody is un-conjugated
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Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
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Options
Purpose Mouse anti-Human Prolactin Receptor Antibody [Sodium Azide Free]
Immunogen Semi-purified human prolactin receptor was used as the immunogen for this anti-Prolactin Receptor antibody.
Specificity Cell surface and cytoplasmic
Purification Semi-purified human prolactin receptor was used as the immunogen for this anti-Prolactin Receptor antibody.
Target
Alternative Name Prolactin receptor (PRLR Antibody Abstract)
Background

Target Description: It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Gene Symbol: PRLR

Gene ID 5618
UniProt P16471
Pathways JAK-STAT Signaling, Response to Growth Hormone Stimulus
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.