KRT1 antibody (Cytokeratin 1)

Details for Product anti-KRT1 Antibody No. ABIN6297655
Antigen
  • CK1
  • EHK
  • EHK1
  • EPPK
  • K1
  • KRT1A
  • NEPPK
  • Krt-2.1
  • Krt2-1
  • Krt86
  • KRT1
  • Kb1
  • KER1
  • CK-1
  • Keratin-1
  • keratin 1
  • KRT1
  • Krt1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
163
57
52
15
15
15
14
12
9
8
4
4
2
1
1
1
1
1
1
1
Host
Mouse
111
75
8
Clonality
Monoclonal
Conjugate
This KRT1 antibody is un-conjugated
13
9
4
4
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
125
95
66
57
41
41
29
21
20
17
5
2
2
2
1
1
Options
Purpose Mouse anti-Human/Mouse/Rat HMW Cytokeratin Antibody [IHC only]
Immunogen Solubilized keratin extract from human stratum corneum was used as the immunogen for this HMW Cytokeratin antibody.
Specificity Cytoplasmic
Purification Solubilized keratin extract from human stratum corneum was used as the immunogen for this HMW Cytokeratin antibody.
Plasmids, Primers & others Plasmids, Primers & others KRT1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Keratin, type II cytoskeletal 1 (KRT1 Antibody Abstract)
Background

Target Description: This antibody recognizes HMW Keratin 1, 5, 10 and 14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. The HMW Cytokeratin antibody shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands, there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this mAb. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. It has also been useful in separating benign from malignant intraductal breast proliferations.

Gene Symbol: KRT1///KRTA

Gene ID 3848
UniProt P04264
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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