CD44 antibody (CD44)

Details for Product anti-CD44 Antibody No. ABIN6297694
Antigen
  • CDW44
  • CSPG8
  • ECMR-III
  • HCELL
  • HUTCH-I
  • IN
  • LHR
  • MC56
  • MDU2
  • MDU3
  • MIC4
  • Pgp1
  • AU023126
  • AW121933
  • AW146109
  • HERMES
  • Ly-24
  • Pgp-1
  • CD44A
  • METAA
  • RHAMM
  • XCD44
  • cd44
  • cdw44
  • cspg8
  • ecmr-iii
  • hcell
  • lhr
  • mc56
  • mdu2
  • mdu3
  • mic4
  • mutch-i
  • pgp1
  • CD44 molecule (Indian blood group)
  • CD44 antigen
  • CD44 molecule (Indian blood group) S homeolog
  • CD44
  • Cd44
  • cd44.S
Reactivity
Baboon, Green monkey (Chlorocebus), Human
816
354
173
48
48
47
40
30
29
25
21
14
11
10
10
6
5
4
2
1
1
1
1
1
1
1
1
1
Host
Mouse
651
229
206
12
2
Clonality
Monoclonal
Conjugate
This CD44 antibody is un-conjugated
146
89
77
44
11
11
10
8
8
8
8
7
7
6
6
6
6
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
691
415
324
230
185
180
177
114
40
40
34
32
21
19
16
13
8
6
5
3
3
3
3
1
1
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1
Options
Purpose Mouse anti-Human/Baboon/Green Monkey CD44 Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for this anti-CD44 antibody.
Specificity Cell surface
Purification Stimulated human leukocytes were used as the immunogen for this anti-CD44 antibody.
Antigen
Alternative Name CD44 antigen (CD44 Antibody Abstract)
Background

Target Description: Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes. Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Gene Symbol: CD44///LHR///MDU2///MDU3///MIC4

Gene ID 960
UniProt P16070
Pathways Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Functional Studies: Order Ab without BSA/azide
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.