Immunoglobulin kappa Variable 1D-16 (IGKV1D-16) antibody

Details for Product No. ABIN6297706
Antigen
  • IGKV1D16
  • L15
  • L15a
  • immunoglobulin kappa variable 1D-16
  • IGKV1D-16
Reactivity
Human
14
Host
Mouse
14
Clonality
Monoclonal
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
13
8
6
4
1
Options
Purpose Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]
Immunogen Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.
Specificity Cell surface, cytoplasmic and secreted
Purification Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.
Antigen
Alternative Name Immunoglobulin kappa variable 1D-16
Background

Target Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene Symbol: IGKV1D-16///IGKC

Gene ID 3514
UniProt P01601, P01834
Application Notes Flow Cytometry: 0.5-2.0 μg/million cells in 0.1ml
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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