IGKV1D-16 antibody
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- Target See all IGKV1D-16 products
- IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
- Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IGKV1D-16 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB)
- Purpose
- Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]
- Specificity
- Cell surface, cytoplasmic and secreted
- Purification
- Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.
- Immunogen
- Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.
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- Application Notes
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Flow Cytometry: 0.5-2.0 μg/million cells in 0.1ml
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
- Alternative Name
- Immunoglobulin kappa variable 1D-16 (IGKV1D-16 Products)
- Synonyms
- IGKV1D16 antibody, L15 antibody, L15a antibody, immunoglobulin kappa variable 1D-16 antibody, IGKV1D-16 antibody
- Background
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Target Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Gene Symbol: IGKV1D-16///IGKC
- Gene ID
- 3514
- UniProt
- P01601, P01834
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