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IGKV1D-16 antibody

IGKV1D-16 Reactivity: Human IHC, FACS, WB, IF Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6296346
  • Target See all IGKV1D-16 products
    IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
    Reactivity
    Human
    Host
    • 1
    Mouse
    Clonality
    • 1
    Monoclonal
    Conjugate
    • 1
    This IGKV1D-16 antibody is un-conjugated
    Application
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]
    Specificity
    Cell surface, cytoplasmic and secreted
    Purification
    Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.
    Immunogen
    Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.
  • Application Notes
    FACS: 0.5-2.0 μg/million cells
    IF: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    Preservative
    Azide free
    Storage
    4 °C,-20 °C
    Storage Comment
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
    Alternative Name
    Immunoglobulin kappa variable 1D-16 (IGKV1D-16 Products)
    Synonyms
    IGKV1D16 antibody, L15 antibody, L15a antibody, immunoglobulin kappa variable 1D-16 antibody, IGKV1D-16 antibody
    Background

    Target Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

    Gene Symbol: IGKV1D-16///IGKC

    Gene ID
    3514
    UniProt
    P01601, P01834
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