KRT18 antibody (Keratin 18)

Details for Product anti-KRT18 Antibody No. ABIN6297738
Antigen
  • CK18
  • K18
  • Krt1-18
  • CYK18
  • DreK18
  • cb83
  • dapk1
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • krt18
  • MGC64569
  • MGC75922
  • KRT18
  • keratin 18
  • keratin 18, type I L homeolog
  • keratin 18, type I
  • keratin, type I cytoskeletal 18
  • K18, simple type I keratin
  • Keratin, type I cytoskeletal 18
  • Krt18
  • KRT18
  • krt18
  • krt18.L
  • LOC700569
  • LOC100136778
  • k1c18
  • LOC100008885
Reactivity
Human
892
230
221
126
95
64
63
52
48
37
35
33
33
33
23
14
11
9
6
3
2
2
2
1
1
Host
Mouse
593
334
14
7
4
2
1
Clonality
Monoclonal
Conjugate
This KRT18 antibody is un-conjugated
55
43
18
11
11
11
11
11
11
10
9
9
8
8
8
8
8
8
8
8
8
8
8
8
8
8
3
3
3
3
3
2
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
585
402
373
369
246
204
170
87
78
76
41
40
30
18
14
11
2
1
Options
Purpose Mouse anti-Human Cytokeratin 18 Antibody [Sodium Azide Free]
Immunogen The human breast cancer cell line PMC-42 was used as the immunogen for this Cytokeratin 18 antibody.
Specificity Cytoplasmic
Purification The human breast cancer cell line PMC-42 was used as the immunogen for this Cytokeratin 18 antibody.
Plasmids, Primers & others Plasmids, Primers & others KRT18 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Keratin, type I cytoskeletal 18 (KRT18 Antibody Abstract)
Background

Target Description: This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Gene Symbol: KRT18///CYK18///PIG46

Gene ID 3875
UniProt P05783
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.