CD20 antibody (Membrane-Spanning 4-Domains, Subfamily A, Member 1) (PE)

Details for Product anti-MS4A1 Antibody No. ABIN6297750
Antigen
  • B1
  • Bp35
  • CD20
  • CVID5
  • LEU-16
  • MS4A2
  • S7
  • AA960661
  • Cd20
  • Ly-44
  • Ms4a2
  • MS4A1
  • bp35
  • cd20
  • ms4a2
  • leu-16
  • ms4a4c
  • cd20-like
  • membrane spanning 4-domains A1
  • membrane-spanning 4-domains, subfamily A, member 1
  • B-lymphocyte antigen CD20
  • MS4A1
  • Ms4a1
  • ms4a1
  • LOC101694281
Reactivity
Human
803
83
48
35
14
11
10
8
7
6
5
3
1
Host
Mouse
624
189
8
5
3
1
1
1
Clonality
Monoclonal
Conjugate
This CD20 antibody is conjugated to PE
63
62
50
42
20
16
10
9
7
7
6
6
6
6
6
6
6
6
6
6
6
6
5
5
5
5
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
537
213
197
179
113
100
97
60
43
28
23
20
14
13
10
9
6
3
2
2
2
1
1
Options
Purpose Mouse anti-Human CD20 Antibody [PE Conjugated]
Immunogen The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
Specificity Predominantly cell surface with some cytoplasmic
Purification The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
Plasmids, Primers & others Plasmids, Primers & others CD20 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name B-lymphocyte antigen CD20 (MS4A1 Antibody Abstract)
Background

Target Description: This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.

Gene Symbol: MS4A1///CD20

Gene ID 931
UniProt P11836
Application Notes Flow Cytometry: 5 µL per test per one million cells in 0.1 mL (or 5 µL per 100 µL of whole blood)
Immunofluorescence: 1:50-1:100
Restrictions For Research Use only
Buffer In 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment 2-8°C. The conjugate is light-sensitive, protect from light.
Did you look for something else?