Actin, gamma 1 antibody (Biotin)

Catalog No. ABIN6297828

Product Details anti-Actin, gamma 1 Antibody (Biotin)

Target: Actin, gamma 1 (ACTG1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin, gamma 1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Purpose: Rabbit anti-Human ACTG Biotinylated Antibody

Immunogen: This antibody was produced from antiserum of rabbits immunized with a recombinant protein immunogen. The IgG fraction was purified by Protein G/A affinity chromatography.

Application Details

Application Notes: ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)

Restrictions: For Research Use only

Handling

Reconstitution: A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: -20°C

Target Details for Actin, gamma 1

Target: Actin, gamma 1 (ACTG1)

Alternative Name: ACTG (ACTG1 Products)

Background:

Target Description: Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

UniProt: P63261

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization