PTP4A3 antibody (Protein Tyrosine Phosphatase Type IVA, Member 3)

Details for Product anti-PTP4A3 Antibody No. ABIN6297877
Antigen
  • PRL-3
  • PRL-R
  • PRL3
  • wu:fc54b05
  • wu:fv52d11
  • zgc:77109
  • prl-3
  • prl3
  • ptpcaax3
  • PTP4A3
  • AV088979
  • Prl-3
  • pPtp4a3
  • protein tyrosine phosphatase type IVA, member 3
  • protein tyrosine phosphatase type IVA, member 3 L homeolog
  • protein tyrosine phosphatase 4a3
  • PTP4A3
  • ptp4a3
  • ptp4a3.L
  • Ptp4a3
Reactivity
Human, Mouse (Murine)
89
44
25
4
3
3
3
3
2
1
1
1
Host
Rabbit
84
5
Clonality
Polyclonal
Conjugate
This PTP4A3 antibody is un-conjugated
7
5
5
5
4
4
2
2
2
2
2
2
1
Application
73
35
19
6
5
5
3
2
2
2
1
1
Options
Purpose Rabbit Anti-PRL3 Antibody
Immunogen This PRL3 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL3.
Plasmids, Primers & others Plasmids, Primers & others PTP4A3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PRL3 (PTP4A3 Antibody Abstract)
Background

Target Description: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.

Gene Symbol: PTP4A3

Gene ID 11156
UniProt O75365
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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