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SMAD2 antibody

SMAD2 Reactivity: Human, Mouse, Rat Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6298099
  • Target See all SMAD2 Antibodies
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Reactivity
    • 236
    • 150
    • 117
    • 12
    • 12
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 239
    • 10
    Rabbit
    Clonality
    • 213
    • 36
    Polyclonal
    Conjugate
    • 127
    • 18
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    This SMAD2 antibody is un-conjugated
    Application
    Please inquire
    Purpose
    Rabbit Anti-Smad2 (Ab-465) Antibody,
    Top Product
    Discover our top product SMAD2 Primary Antibody
  • Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    2-8°C (short-term), -20°C (long-term)
  • Target
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Alternative Name
    Smad2 (SMAD2 Products)
    Synonyms
    JV18 antibody, JV18-1 antibody, MADH2 antibody, MADR2 antibody, hMAD-2 antibody, hSMAD2 antibody, jv18 antibody, Xmad2 antibody, madh2 antibody, madr2 antibody, XSmad2 antibody, hmad-2 antibody, hsmad2 antibody, jv18-1 antibody, smad-2 antibody, fj43c06 antibody, wu:fj43c06 antibody, 7120426M23Rik antibody, Madh2 antibody, Madr2 antibody, Smad-2 antibody, mMad2 antibody, MAD homolog 2 antibody, Mothers against DPP homolog 2 antibody, SMAD 2 antibody, Smad2 antibody, SMAD family member 2 antibody, SMAD family member 2-Z antibody, SMAD family member 2 S homeolog antibody, SMAD2 antibody, SMAD2Z antibody, smad2 antibody, smad2.S antibody, Smad2 antibody
    Background

    Target Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    Gene Symbol: SMAD2

    Gene ID
    4087
    UniProt
    Q15796
    Pathways
    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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