SMAD2 antibody (SMAD, Mothers Against DPP Homolog 2)

Details for Product anti-SMAD2 Antibody No. ABIN6298099
Antigen
  • JV18
  • JV18-1
  • MADH2
  • MADR2
  • hMAD-2
  • hSMAD2
  • jv18
  • Xmad2
  • madh2
  • madr2
  • XSmad2
  • hmad-2
  • hsmad2
  • jv18-1
  • smad-2
  • fj43c06
  • wu:fj43c06
  • 7120426M23Rik
  • Madh2
  • Madr2
  • Smad-2
  • mMad2
  • MAD homolog 2
  • Mothers against DPP homolog 2
  • SMAD 2
  • Smad2
  • SMAD family member 2
  • SMAD family member 2-Z
  • SMAD family member 2 S homeolog
  • SMAD2
  • SMAD2Z
  • smad2
  • smad2.S
  • Smad2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
480
299
269
26
19
18
18
16
13
11
10
10
7
6
6
4
1
1
1
1
1
Host
Rabbit
436
54
7
Clonality
Polyclonal
Conjugate
This SMAD2 antibody is un-conjugated
26
13
12
10
10
10
10
10
10
7
7
7
2
2
2
2
2
2
Application
397
209
116
82
62
27
27
26
25
19
18
5
5
3
3
2
1
Options
Purpose Rabbit Anti-Smad2 (Ab-465) Antibody,
Plasmids, Primers & others Plasmids, Primers & others SMAD2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Smad2 (SMAD2 Antibody Abstract)
Background

Target Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Gene Symbol: SMAD2

Gene ID 4087
UniProt Q15796
Pathways Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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