ERI1 antibody (Exoribonuclease 1)

Details for Product anti-ERI1 Antibody No. ABIN6298170
Antigen
  • THEX1
  • thex1
  • zgc:110635
  • hexo
  • Eri-1
  • 3'HEXO
  • HEXO
  • 3'hexo
  • 3110010F15Rik
  • Thex1
  • eri-1
  • RGD1308378
  • exoribonuclease 1
  • three prime repair exonuclease 1
  • exoribonuclease 1 L homeolog
  • 3'-5' exonuclease eri-1
  • ERI1
  • CpipJ_CPIJ003945
  • eri1
  • eri1.L
  • Eri1
  • eri-1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
70
26
24
5
3
3
2
2
2
1
Host
Rabbit
68
4
Clonality
Polyclonal
Conjugate
This ERI1 antibody is un-conjugated
5
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
52
32
13
11
4
4
3
2
2
1
1
Options
Purpose Rabbit Anti-ERI1 Antibody,
Plasmids, Primers & others Plasmids, Primers & others ERI1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name ERI1 (ERI1 Antibody Abstract)
Background

Target Description: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication- dependent histone pre-mRNAs.

Gene Symbol: ERI1
Gene ID 90459
UniProt Q8IV48
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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