Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibody

Details for Product No. ABIN6298210
Target
Reactivity
Human, Mouse, Rat
139
92
91
5
4
3
2
2
2
1
1
1
1
1
Host
Rabbit
123
14
7
2
Clonality
Polyclonal
Conjugate
Un-conjugated
10
7
5
5
5
5
5
5
5
3
3
3
3
3
1
1
1
Application
91
48
43
39
28
15
9
9
7
3
1
1
Options
Purpose Rabbit Anti-p130 Cas (Ab-410) Antibody,
Target
Alternative Name p130 Cas (BCAR1 Antibody Abstract)
Background

Target Description: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Gene Symbol: BCAR1
Gene ID 9564
UniProt P56945
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)