SF3A3 antibody (Middle Region)

Catalog No. ABIN633429

Product Details anti-SF3A3 Antibody

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: SF3 A3 antibody was raised against the middle region of SF3 3

Purification: Affinity purified

Immunogen: SF3 A3 antibody was raised using the middle region of SF3 3 corresponding to a region with amino acids THENVQRKQARTGEEREEEEEEQISESESEDEENEIIYNPKNLPLGWDGK

Application Details

Application Notes: WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SF3A3 Blocking Peptide, catalog no. 33R-9103, is also available for use as a blocking control in assays to test for specificity of this SF3A3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SF0 3 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Alternative Name: SF3A3 (SF3A3 Products)

Synonyms: PRP9 antibody, PRPF9 antibody, SAP61 antibody, SF3a60 antibody, 4930512K19Rik antibody, 60kDa antibody, LRRGT00093 antibody, wu:fi15a06 antibody, wu:fj94f01 antibody, zgc:110227 antibody, splicing factor 3a subunit 3 antibody, splicing factor 3a, subunit 3, 60kDa antibody, splicing factor 3a, subunit 3 antibody, splicing factor 3a subunit 3 S homeolog antibody, SF3A3 antibody, Sf3a3 antibody, sf3a3.S antibody, sf3a3 antibody

Background: SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.

Molecular Weight: 59 kDa (MW of target protein)

Pathways: Ribonucleoprotein Complex Subunit Organization