TRF1 antibody (Telomeric Repeat Binding Factor (NIMA-Interacting) 1)

Details for Product anti-TERF1 Antibody No. ABIN6566478
Antigen
Reactivity
Human, Mouse (Murine)
143
45
24
1
1
1
1
1
1
Host
Rabbit
118
22
8
Clonality
Polyclonal
Conjugate
This TRF1 antibody is un-conjugated
10
6
5
5
5
5
5
5
3
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
101
66
28
16
13
13
8
6
4
2
2
1
Options
Immunogen Recombinant protein of human TERF1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name TERF1 (TERF1 Antibody Abstract)
Background

Synonyms: hTRF1 AS,NIMA interacting protein 2,NIMA-interacting protein 2,PIN 2,PIN2,t TRF1,Telomeric protein Pin2,Telomeric protein Pin2/TRF1,Telomeric repeat binding factor (NIMA interacting) 1,Telomeric repeat binding factor 1,Telomeric repeat binding protein 1,Telomeric repeat-binding factor 1,TERF 1,Terf1,TERF1,TRBF 1,TRBF1,TRF 1,TRF,TTAGGG repeat binding factor 1,TTAGGG repeat-binding factor 1

Background: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Molecular Weight

Observed_MW: 62kDa

Calculated_MW: 48kDa/50kDa

Gene ID 7013
UniProt P54274
Pathways Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1) antibody (ABIN6566478) Western blot analysis of extracts of mouse eye, using TERF1 antibody.
Image no. 2 for anti-Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1) antibody (ABIN6566478) Immunohistochemistry of paraffin-embedded human gastric cancer using TERF1 antibody.