TRF1 antibody (AA 240-419)

Catalog No. ABIN1683138

The Rabbit Polyclonal anti-TRF1 antibody (ABIN1683138) specifically detects TRF1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for TRF1 antibody (AA 240-419) (ABIN1683138)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRF1 Antibody

Binding Specificity: AA 240-419

Sequence: IKSYVNYVLS EKSSTFLMKA AAKVVESKRT RTITSQDKPS GNDVEMETEA NLDTRKRSHK NLFLSKLQHG TQQQDLNKKE RRVGTPQSTK KKKESRRATE SRIPVSKSQP VTPEKHRARK RQAWLWEEDK NLRSGVRKYG EGNWSKILLH YKFNNRTSVM LKDRWRTMKK LKLISSDSED

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-419 of human TERF1 (NP_003209.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: TERF1

Background: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.,TERF1,PIN2,TRBF1,TRF,TRF1,hTRF1-AS,t-TRF1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,TERF1

Molecular Weight: 48 kDa/50 kDa

Gene ID: 7013

UniProt: P54274

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity