Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) antibody

Details for Product No. ABIN6566491
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
181
86
61
7
6
6
5
5
5
4
4
3
2
Host
Rabbit
168
34
Clonality
Polyclonal
Conjugate
Un-conjugated
11
11
10
10
8
8
3
3
3
3
3
3
2
2
2
2
2
Application
Western Blotting (WB)
151
85
34
31
26
9
4
4
4
1
1
Options
Immunogen Recombinant protein of human TEC
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name TEC (NR4A3 Antibody Abstract)
Background

Synonyms: MGC126760,MGC126762,PSCTK4 ,Tec,Tec protein tyrosine kinase,TEC,Tyrosine protein kinase,Tyrosine-protein kinase Tec

Background: The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Molecular Weight

Observed_MW: 68kDa

Calculated_MW: 73kDa

Gene ID 7006
UniProt P42680
Pathways Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) antibody (ABIN6566491) Western blot analysis of extracts of various cell lines, using TEC antibody.