BAK1 antibody (BCL2-Antagonist/killer 1)

Details for Product anti-BAK1 Antibody No. ABIN6566497
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
179
68
37
6
2
1
1
1
1
Host
Rabbit
158
12
9
1
Clonality
Polyclonal
Conjugate
This BAK1 antibody is un-conjugated
7
4
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
141
78
60
32
24
16
15
13
8
6
4
2
1
1
Options
Immunogen A synthetic peptide of human BAK1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name BAK1 (BAK1 Antibody Abstract)
Background

Synonyms: Apoptosis regulator BAK,BAK,BAK like,Bak NT,BAK,Bak1,Bcl 2 homologous antagonist/killer,Bcl 2 like 7 protein,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7,BCL2 antagonist/killer 1,Bcl2 like 7 Protein,Bcl2-L-7,BCL2L7,CDN1,Cell death inhibitor 1,MGC117255,MGC3887,NBak,Pro apoptotic protein BAK

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Molecular Weight

Observed_MW: 26kDa

Calculated_MW: 16kDa/23kDa

Gene ID 578
UniProt Q16611
Pathways Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded protein response
Application Notes WB 1:500 - 1:2000 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-BCL2-Antagonist/killer 1 (BAK1) antibody (ABIN6566497) Western blot analysis of extracts of various cell lines, using BAK1 Antibody.
Image no. 2 for anti-BCL2-Antagonist/killer 1 (BAK1) antibody (ABIN6566497) Immunofluorescence analysis of HeLa cells using BAK1 antibody.