CDK1 antibody (Cyclin-Dependent Kinase 1)

Details for Product anti-CDK1 Antibody No. ABIN6566509
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
657
366
331
37
37
30
25
17
17
15
15
11
10
9
9
8
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
537
147
Clonality
Polyclonal
Conjugate
This CDK1 antibody is un-conjugated
35
21
20
15
14
14
13
13
13
13
13
13
5
5
5
5
5
3
3
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
541
250
191
100
98
76
66
59
33
18
12
9
7
7
6
5
3
2
2
2
2
1
1
1
Options
Immunogen A synthetic peptide of human CDK1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CDK1 (CDK1 Antibody Abstract)
Background

Synonyms: Cdc 2,Cdc2,CDC28A,CDK 1,CDK1,CDK1,CDKN1,CELL CYCLE CONTROLLER CDC2,Cell division control protein 2,Cell division control protein 2 homolog,Cell division cycle 2 G1 to S and G2 to M,Cell division protein kinase 1,Cell Divsion Cycle 2 Protein,Cyclin Dependent Kinase 1,Cyclin-dependent kinase 1,DKFZp686L20222,MGC111195,p34 Cdk1,p34 protein kinase,P34CDC2

Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 32kDa

Calculated_MW: 27kDa/34kDa

Gene ID 983
UniProt P06493
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Cyclin-Dependent Kinase 1 (CDK1) antibody (ABIN6566509) Western blot analysis of extracts of various cell lines, using CDK1 antibody.
Image no. 2 for anti-Cyclin-Dependent Kinase 1 (CDK1) antibody (ABIN6566509) Immunohistochemistry of paraffin-embedded rat brain using CDK1 antibody.
Image no. 3 for anti-Cyclin-Dependent Kinase 1 (CDK1) antibody (ABIN6566509) Immunohistochemistry of paraffin-embedded mouse brain using CDK1 antibody.
Image no. 4 for anti-Cyclin-Dependent Kinase 1 (CDK1) antibody (ABIN6566509) Immunofluorescence analysis of A549 cells using CDK1 antibody.