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CDK1 Products

(Cyclin-Dependent Kinase 1 (CDK1))

Categories

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured CDK1 Categories

CDK1 Antibodies

High quality antibodies with extensive validation data.

CDK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CDK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC, WB
Validations
  • (6)
Cat. No. ABIN7265020
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, IP, WB
Validations
  • (7)
Cat. No. ABIN7266576
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (11)
  • (4)
Cat. No. ABIN3043473
Quantity 100 μg
Datasheet Datasheet

Recommended CDK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
Cat. No. ABIN6730452
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966161
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955153
Quantity 96 tests
Datasheet Datasheet

Recommended CDK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1348775
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5569585
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5569586
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CDK1 products

Niu, Sun, Liu, Li, Liang, Zhang, Ge, Liu: "Croton tiglium essential oil compounds have anti-proliferative and pro-apoptotic effects in A549 lung cancer cell lines." in: PloS one, Vol. 15, Issue 5, pp. e0231437, (2020) (PubMed).

Zhang, Yao, Luan, Zhao, Jing, Zhang, Hou, Zou: "APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica." in: Scientific reports, Vol. 6, pp. 39047, (2018) (PubMed).

Zhang, Miao, Li, Cui, Ge, Chen: "S-phase kinase-associated protein 2 impairs the inhibitory effects of miR-1236-3p on bladder tumors." in: American journal of translational research, Vol. 10, Issue 3, pp. 731-743, (2018) (PubMed).

Lin, Zhu, Sun, Yang, Sun, Li, Cui, Zheng, Yu: "Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8." in: Oncology letters, Vol. 15, Issue 6, pp. 9436-9442, (2018) (PubMed).

Guo, Lv, Chang, Chen, Lu, Xu, Liu, Pang: "Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder." in: Oncotarget, Vol. 7, Issue 29, pp. 45249-45262, (2018) (PubMed).

Liu, Liu, Wang, Yu, Miao, Liu, Wang, Du, Yang: "Heat shock protein 90α couples with the MAPK-signaling pathway to determine meiotic maturation of porcine oocytes." in: Journal of animal science, Vol. 96, Issue 8, pp. 3358-3369, (2018) (PubMed).

Liu, Fu, Sun, Wang, Geng, Wang, Zou, Bi, Yang et al.: "A New Perspective for Osteosarcoma Therapy: Proteasome Inhibition by MLN9708/2238 Successfully Induces Apoptosis and Cell Cycle Arrest and Attenuates the Invasion Ability of Osteosarcoma Cells in ..." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 2, pp. 451-465, (2017) (PubMed).

Wang, Wang, Liu, Dong, Hu, Miao, Li, Liu, Zhou, Zhang, Ma, Luo: "ATM Signaling Pathway Is Implicated in the SMYD3-mediated Proliferation and Migration of Gastric Cancer Cells." in: Journal of gastric cancer, Vol. 17, Issue 4, pp. 295-305, (2017) (PubMed).

Ghate, Das, Chaudhuri, Panja, Mandal: "Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio." in: Cell death discovery, Vol. 2, pp. 15062, (2016) (PubMed).

Zang, Zhang, Gao, Huang: "Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).

Synonyms and alternative names related to CDK1

cyclin dependent kinase 1 (CDK1), cyclin dependent kinase like 1 (CDKL1), Cell division control protein 2 1 (POPTR_0004s14080g), cyclin-dependent kinase 1 (Cdk1), cyclin-dependent kinase 1 (cdk1), cyclin-dependent kinase 1 S homeolog (cdk1.S), Cyclin-dependent kinase 1 (Cdk1), cell division control 2 (CDC2), cell division control protein2 homolog (cdc2), Cyclin-dependent kinase 1 (cdk-1), cyclin-dependent kinase 1 L homeolog (cdk1.L), cyclin dependent kinase 1 (Cdk1), polymerase (DNA directed), delta 1, catalytic subunit L homeolog (pold1.L), cyclin dependent kinase 1 (cdk1), cyclin-dependent protein kinase Cdk1/Cdc2 (cdc2), 5363, cdc, cdc-2, CDC2, Cdc2, cdc2, cdc2-a, cdc2-b, Cdc2a, CDC2A, cdc2a, CDC2AAT, cdc2Dm, cdc2x1.1, cdc2x1.2, CDC28A, cdc28a, CDCDm, Cdk-1, CDK1, Cdk1, cdk1, CDK1/CDC2, CDK2, CDKA1, CDKA;1, cell division control 2, CG5363, CYCLIN-DEPENDENT KINASE A;1, Dcdc2, dCdk1, Dm cdc2, DmCdc2, Dmcdc2, DmCdk1, Dmel\\CG5363, group 4, l(2)31Eh, p34, P34CDC2, p34cdc2, POL3, pold, PSTAIR, wu:fc30e01, xcdc2, zgc:92032

Protein level used designations for CDK1

  • cell cycle controller CDC2
  • cell division control protein 2 homolog
  • cell division cycle 2, G1 to S and G2 to M
  • cell division protein kinase 1
  • p34 protein kinase
  • cyclin-dependent kinase 1
  • cell cycle p34 CDC2 kinase protein
  • cell division cycle 2 homolog A
  • cell division cycle control protein 2a
  • Cell division cycle control protein 2
  • cell division cycle 2
  • Cell division control protein 2 homolog 1
  • cell division control protein 2-A
  • cell division cycle 2 like
  • cell division protein kinase 1-A
  • cyclin-dependent kinase 1-A
  • p34 protein kinase 1
  • CG5363-PA
  • cdc2 kinase
  • cdc2-PA
  • cyclin dependent kinase
  • cyclin-dependent kinase
  • cell division cycle 2 protein
  • PCO133105
  • PCO133105_ov
  • p34cdc2
  • protein cdc2 kinase
  • putative cyclin-dependent kinase A family protein
  • cell division control protein 2 homolog 2
  • cell division control protein 2-B
  • cell division protein kinase 1-B
  • cyclin-dependent kinase 1-B
  • p34 protein kinase 2
  • DNA polymerase delta
  • DNA-directed DNA polymerase delta 1
  • polymerase (DNA directed), delta 1, catalytic subunit 125kDa
  • Cell division control protein 2 homolog
  • Cell division protein kinase 1
  • Cell division control protein 2
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