Superoxide Dismutase 1, Soluble (SOD1) antibody

Details for Product No. ABIN6566553
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
457
307
287
117
74
62
53
51
51
46
43
42
42
42
31
24
18
18
10
7
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
443
83
13
10
6
4
1
Clonality
Polyclonal
Conjugate
Un-conjugated
39
34
20
12
10
10
7
7
7
7
7
7
7
7
7
7
7
4
4
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
Application
Western Blotting (WB)
486
329
238
130
82
79
52
34
33
21
16
9
6
3
3
3
2
2
2
2
Options
Immunogen Recombinant protein of human SOD1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name SOD1 (SOD1 Antibody Abstract)
Background

Synonyms: ALS,ALS1,Amyotrophic lateral sclerosis 1 adult,Cu/Zn SOD,Cu/Zn superoxide dismutase,Epididymis secretory protein Li 44,HEL S 44,Homodimer,hSod1,Indophenoloxidase A,IPOA,Mn superoxide dismutase,SOD,SOD soluble,SOD1,SOD2,SODC,SODC,Superoxide dismutase [Cu-Zn],Superoxide dismutase 1,Superoxide dismutase 1 soluble,Superoxide dismutase Cu Zn,Superoxide dismutase cystolic

Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Molecular Weight

Observed_MW: 20kDa

Calculated_MW: 15kDa
Gene ID 6647
UniProt P00441
Pathways Sensory Perception of Sound, Transition Metal Ion Homeostasis
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Superoxide Dismutase 1, Soluble (SOD1) antibody (ABIN6566553) Western blot analysis of extracts of various cell lines, using SOD1 antibody.