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Synonyms: CD106,CD106 Antigen,INCAM 100,INCAM-100,L1CAM,MGC99561,V-CAM 1,Vascular Cell Adhesion Molecule 1,Vascular cell adhesion protein 1,VCAM 1,VCAM-1,VCAM1,VCAM1
Background: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.