Progesterone Receptor antibody (PGR)

Details for Product anti-PGR Antibody No. ABIN6566573
Antigen
Reactivity
Human, Rat (Rattus)
668
152
151
25
9
8
7
6
5
3
2
2
2
1
1
1
1
1
Host
Rabbit
405
272
3
1
Clonality
Polyclonal
Conjugate
This Progesterone Receptor antibody is un-conjugated
31
18
17
14
14
14
14
14
14
9
9
9
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Application
Western Blotting (WB)
444
198
167
135
81
67
52
44
24
24
15
11
10
9
3
1
1
1
Options
Immunogen Recombinant protein of human PGR
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PGR (PGR Antibody Abstract)
Background

Synonyms: NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PRA,PRB,PRGR,Progesterone receptor,Progestin receptor form A,Progestin receptor form B

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Molecular Weight

Observed_MW: 100kDa

Calculated_MW: 36kDa/38kDa/82kDa/87kDa/98kDa

Gene ID 5241
UniProt P06401
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
Application Notes WB 1:200 - 1:500
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Progesterone Receptor (PGR) antibody (ABIN6566573) Western blot analysis of extracts of BT-474 cells, using PGR antibody.