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TNFRSF1B antibody

TNFRSF1B Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566586
  • Target See all TNFRSF1B Antibodies
    TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
    Reactivity
    • 84
    • 55
    • 34
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 64
    • 30
    • 8
    • 4
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 59
    • 50
    Polyclonal
    Conjugate
    • 70
    • 15
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This TNFRSF1B antibody is un-conjugated
    Application
    • 68
    • 32
    • 32
    • 31
    • 29
    • 20
    • 18
    • 16
    • 14
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human TNFRSF1B
    Isotype
    IgG
    Top Product
    Discover our top product TNFRSF1B Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000 IF 1:50 - 1:200
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
    Alternative Name
    TNFRSF1B (TNFRSF1B Products)
    Background

    Synonyms: CD120b,p75,p75 TNF receptor,p75TNFR,p80 TNF alpha receptor,p80 TNF-alpha receptor,Soluble TNFR1B variant 1,TBP-2,TBPII,TNF R II,TNF R2,TNF R75,TNF-R2,TNF-RII,TNFBR,TNFR-II,TNFR1B,TNFR2,TNFR80,TNFRII,Tnfrsf1b,TNR1B,Tumor necrosis factor beta receptor,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor type II,Tumor necrosis factor-binding protein 2

    Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

    Molecular Weight

    Observed_MW: 65kDa

    Calculated_MW: 28kDa/48kDa

    Gene ID
    7133
    UniProt
    P20333
    Pathways
    NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
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