Fatty Acid Synthase antibody

Catalog No. ABIN6566594

Product Details anti-Fatty Acid Synthase Antibody

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity: This antibody ist KO validated.

Purification: Affinity purification

Grade: KO Validated

Immunogen: Recombinant fusion protein of human Fatty Acid Synthase (NP_004095.4).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: Fatty Acid Synthase (FASN Products)

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Molecular Weight:

Observed_MW: 275kDa

Calculated_MW: 273kDa

Gene ID: 2194

UniProt: P49327

Pathways: AMPK Signaling