Fatty Acid Synthase antibody (FASN)

Details for Product anti-FASN Antibody No. ABIN6566594
Antigen
Reactivity
Human
149
79
62
4
3
3
2
2
2
2
2
2
1
1
1
Host
Rabbit
132
26
4
Clonality
Polyclonal
Conjugate
This Fatty Acid Synthase antibody is un-conjugated
6
5
5
5
5
5
5
2
2
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
116
49
39
32
27
22
18
13
11
6
4
3
2
1
Options
Immunogen Recombinant protein of human FASN
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name FASN (FASN Antibody Abstract)
Background

Synonyms: [Acyl-carrier-protein] S acetyltransferase,[Acyl-carrier-protein] S malonyltransferase,3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase,3-oxoacyl-[acyl-carrier-protein] reductase,3-oxoacyl-[acyl-carrier-protein] synthase,Enoyl-[acyl-carrier-protein] reductase,FAS,FAS,FASN,Fatty acid synthase,MGC14367,MGC15706,OA 519,Oleoyl-[acyl-carrier-protein] hydrolase,SDR27X1,Short chain dehydrogenase/reductase family 27X member 1

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Molecular Weight

Observed_MW: 275kDa

Calculated_MW: 273kDa
Gene ID 2194
UniProt P49327
Pathways AMPK Signaling
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Fatty Acid Synthase (FASN) antibody (ABIN6566594) Immunohistochemistry of paraffin-embedded human colon using FASN antibody.
Image no. 2 for anti-Fatty Acid Synthase (FASN) antibody (ABIN6566594) Immunofluorescence analysis of A549 cells using FASN antibody.
Image no. 3 for anti-Fatty Acid Synthase (FASN) antibody (ABIN6566594) Western blot analysis of extracts of H460 cells, using FASN antibody.
Image no. 4 for anti-Fatty Acid Synthase (FASN) antibody (ABIN6566594) Immunohistochemistry of paraffin-embedded human gastric cancer using FASN antibody.