Endonuclease G antibody (ENDOG)

Details for Product anti-ENDOG Antibody No. ABIN6566623
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
129
70
69
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
96
36
Clonality
Polyclonal
Conjugate
This Endonuclease G antibody is un-conjugated
5
4
4
4
4
4
4
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
94
37
16
14
13
11
10
4
2
2
1
1
Options
Immunogen Recombinant protein of human ENDOG
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name ENDOG (ENDOG Antibody Abstract)
Background

Synonyms: EndoG,Endonuclease G,Endonuclease G mitochondrial,EndonucleaseG,FLJ27463,Mitochondrial endonuclease G,NUCG

Background: The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.

Molecular Weight

Observed_MW: 33kDa

Calculated_MW: 32kDa

Gene ID 2021
UniProt Q14249
Pathways Apoptosis
Application Notes WB 1:200 - 1:500 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Endonuclease G (ENDOG) antibody (ABIN6566623) Western blot analysis of extracts of various cell lines, using ENDOG antibody.
Image no. 2 for anti-Endonuclease G (ENDOG) antibody (ABIN6566623) Immunohistochemistry of paraffin-embedded mouse lung using ENDOG antibody.
Image no. 3 for anti-Endonuclease G (ENDOG) antibody (ABIN6566623) Immunohistochemistry of paraffin-embedded mouse kidney using ENDOG antibody.